| Date | Location | Result | |
| Apr 30, 2022 | Salt Lake City, Utah | Utah 16, Detroit Mercy 9 | Box score |
| Apr 23, 2022 | Birmingham, Mich. | Detroit Mercy 13, Cleveland State 12 | Box score |
| Apr 16, 2022 | Louisville, KY | Bellarmine 13, Detroit Mercy 8 | Box score |
| Apr 9, 2022 | Birmingham, Mich. | Air Force 13, Detroit Mercy 4 | Box score |
| Apr. 2, 2022 | Birmingham, Mich. | Robert Morris 12, Detroit Mercy 5 | Box score |
| Mar 26, 2022 | High Point, NC | High Point 18, Detroit Mercy 8 | Box score |
| Mar 12, 2022 | SEAHOLM HIGH SCHOOL | Detroit Mercy 16, VMI 11 | Box score |
| Mar 05, 2022 | Milwaukee, Wis. | Marquette 13, Detroit Mercy 7 | Box score |
| Feb 19, 2022 | South Bend, IN | Notre Dame 24, Detroit Mercy 2 | Box score |
| Feb 12, 2022 | Ann Arbor, Mich. | Michigan 21, Detroit Mercy 5 | Box score |
| Feb 05, 2022 | Columbus, Ohio | Ohio State 18, Detroit Mercy 7 | Box score |